If you have Windows servers that are exposed directly to the Internet so that their Service service is exposed, make you you get MS06-040 that was just released applied to your servers quickly. There is active exploitation and public exploit code being used out there.
UPDATE: MS has posted Security Advisory 992537 related to this vunerability also.
Technorati Tags: MS06-040, Security+patch, Windows+server, US-CERT
Wading Through 